Antibodies against a Tick Protein, Salp15, Protect Mice from the Lyme Disease Agent

Article, Other literature type English OPEN
Dai, Jianfeng; Wang, Penghua; Adusumilli, Sarojini; Booth, Carmen J.; Narasimhan, Sukanya; Anguita, Juan; Fikrig, Erol;
  • Publisher: Elsevier BV
  • Journal: Cell Host & Microbe,volume 6,issue 5,pages482-492 (issn: 1931-3128)
  • Related identifiers: pmc: PMC2843562, doi: 10.1016/j.chom.2009.10.006
  • Subject: Molecular Biology | Immunology and Microbiology(all) | Article | Cancer Research
    mesheuropmc: bacterial infections and mycoses

Traditionally, vaccines directly target a pathogen or microbial toxin. Lyme disease, caused by Borrelia burgdorferi, is a tick-borne illness for which a human vaccine is not currently available. B. burgdorferi binds a tick salivary protein, Salp15, during transmission f... View more
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