Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency
Yin, HaiFang; Boisguerin, Prisca; Moulton, Hong M; Betts, Corinne; Seow, Yiqi; Boutilier, Jordan; Wang, Qingsong; Walsh, Anthony; Lebleu, Bernard; Wood, Matthew JA;
- Publisher: Elsevier
- Journal: Molecular Therapy: Nucleic Acids,volume 2,issue 9,pagee124 (issn: 2162-2531, eissn: 2162-2531)
Related identifiers: , - Subject: Original Article | RM1-950 | chimeric peptide conjugate | antisense oligonucleotide | exon skipping | Therapeutics. Pharmacology | Duchenne muscular dystrophy
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity of morpholino phosphorodiam... View more
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UNIVERSITY OF OXFORD 90%OREGON STATE UNIVERSITY 90%University Montpellier 2 France88%University of Montpellier 1 88%University Of Oxford 90%University of Oxford ( University of Oxford ) United KingdomWebsite url: http://www.ox.ac.uk/90%Tianjin Medical University ( TMU ) ChinaWebsite url: http://www.tmu.edu.cn/s/2/t/250/p/3/c/1080/list.htm90%Université de Montpellier ( UNIVERSITE DE MONTPELLIER ) FranceWebsite url: https://www.umontpellier.fr/90%Sigma Labs (United States) ( Sigma Labs (United States) ) United StatesWebsite url: http://www.sigmalabsinc.com/89% - Metrics
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