Canalization of C. elegans Vulva Induction against Anatomical Variability

Article English OPEN
Huelsz-Prince, Guizela; van Zon, Jeroen Sebastiaan;
  • Publisher: Elsevier BV
  • Journal: Cell Systems,volume 4,issue 2,pages219-230,000,000 (issn: 2405-4712, eissn: 2405-4720)
  • Related identifiers: pmc: PMC5330807, doi: 10.1016/j.cels.2017.01.009
  • Subject: development | C. elegans | cell signaling | robustness | cell migration | stochasticity | single-molecule FISH | variability | Delta-Notch | morphogen gradient | Article

Summary It is a fundamental open question as to how embryos develop into complex adult organisms with astounding reproducibility, particularly because cells are inherently variable on the molecular level. During C. elegans vulva induction, the anchor cell induces cell f... View more
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