Atovaquone and proguanil hydrochloride compared with chloroquine or pyrimethamine/sulfadoxine for treatment of acute Plasmodium falciparum malaria in Peru

Article English OPEN
A. Llanos-Cuentas ; P. Campos ; M. Clendenes ; C. J. Canfield ; D. B. A. Hutchinson
  • Publisher: Elsevier
  • Journal: Brazilian Journal of Infectious Diseases (issn: 1678-4391, eissn: 1678-4391)
  • Related identifiers: doi: 10.1590/S1413-86702001000200004
  • Subject: proguanil | chloroquine resistance | RC109-216 | atovaquone | Infectious and parasitic diseases | Malarone | Peru
    mesheuropmc: parasitic diseases

The efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (MalaroneTM) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru. Patients were initially randomized to recei... View more
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