A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus
Article, Other literature type
Chambers, D M
Copeland, Neal G
Gilbert, Debra J
Jenkins, Nancy A
Research Article | DNA/genetics | DNA/isolation & purification | Oxidoreductases | RNA, Messenger/genetics | Molecular Sequence Data | Mice | Isomerases/genetics | Mice, Inbred C57BL | Amino Acid Sequence | Epidermal Growth Factor/genetics | Intramolecular Oxidoreductases | Sequence Homology, Nucleic Acid | Animals | Base Sequence | Female | Polymerase Chain Reaction | Proteins/genetics | Muridae | Monophenol Monooxygenase/genetics | Mutation | Membrane Glycoproteins | Mice, Mutant Strains | Chromosome Mapping | Crosses, Genetic | Male
We have cloned and sequenced mouse cDNAs corresponding to a third member of a family of melanocyte-specific mRNAs, which encode tyrosinase and related proteins. This new member, tyrosinase-related protein-2 (TRP-2), has approximately 40% amino acid identity with the two...