DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

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Ligthart, S. ; Marzi, C. ; Aslibekyan, S. ; Mendelson, M. ; Conneely, K. ; Tanaka, T. ; Colicino, E. ; Waite, L. ; Joehanes, R. ; Guan, W. ; Brody, J. ; Elks, C. ; Marioni, R. ; Jhun, M. ; Agha, G. ; Bressler, J. ; Ward-Caviness, C. ; Chen, B. ; Huan, T. ; Bakulski, K. ; Salfati, E. ; Wahl, S. ; Schramm, K. ; Sha, J. ; Hernandez, D. ; Just, A. ; Smith, J. ; Sotoodehnia, N. ; Pilling, L. ; Pankow, J. ... view all 86 authors (2016)

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade inflammation may reveal novel pathways or therapeuti... View more
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