Mouse Pancreas Tissue Slice Culture Facilitates Long-Term Studies of Exocrine and Endocrine Cell Physiology in situ

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Marciniak, Anja; Selck, Claudia; Friedrich, Betty; Speier, Stephan;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 8,issue 11 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3817072, doi: 10.1371/journal.pone.0078706
  • Subject: Q | R | Research Article | Pancreas, Insulin, Cell physiology, Endocrine cells, Glucose, Endocrine physiology, Secretion, Cell staining | Science | Medicine | Pankreas, regenertative Therapie, Diabetes
    • ddc: ddc:610

Studies on pancreatic cell physiology rely on the investigation of exocrine and endocrine cells in vitro. Particularly, in the case of the exocrine tissue these studies have suffered from a reduced functional viability of acinar cells in culture. As a result not only in... View more
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