Advances in the Genetics of Hypertension: The Effect of Rare Variants

Article English OPEN
Russo, Alessia; Di Gaetano, Cornelia; Cugliari, Giovanni; Matullo, Giuseppe;
  • Publisher: MDPI AG
  • Journal: International Journal of Molecular Sciences,volume 19,issue 3 (issn: 1422-0067, eissn: 1422-0067)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC5877549, doi: 10.3390/ijms19030688
  • Subject: rare variants | Chemistry | blood pressure | rare-variants association testing | sequence kernel association test | next-generation sequencing | Blood pressure; Burden test; Essential hypertension; Exome microarray; Genome-wide association studies; Next-generation sequencing; Rare variants; Rare-variants association testing; Sequence kernel association test; Catalysis; Molecular Biology; Spectroscopy; Computer Science Applications1707 Computer Vision and Pattern Recognition; Physical and Theoretical Chemistry; Organic Chemistry; Inorganic Chemistry | QD1-999 | essential hypertension | burden test | exome microarray | QH301-705.5 | Review | genome-wide association studies | Biology (General)

Worldwide, hypertension still represents a serious health burden with nine million people dying as a consequence of hypertension-related complications. Essential hypertension is a complex trait supported by multifactorial genetic inheritance together with environmental ... View more
Share - Bookmark