Reduction of the Nitro Group to Amine by Hydroiodic Acid to Synthesize o-Aminophenol Derivatives as Putative Degradative Markers of Neuromelanin
Other literature type, Article
- Publisher: Multidisciplinary Digital Publishing Institute
aminohydroxyphenylacetic acid | HI reduction | Organic chemistry | QD241-441 | neuromelanin | aminohydroxyethylbenzene | aminohydroxyphenylethylamine | Parkinson’s disease
Neuromelanin (NM) is produced in dopaminergic neurons of the substantia nigra (SN) and in noradrenergic neurons of the locus coeruleus (LC). The synthesis of NM in those neurons is a component of brain aging and there is the evidence that this pigment can be involved i...