Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells

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Soichiro Sonoda; Haruyoshi Yamaza; Lan Ma; Yosuke Tanaka; Erika Tomoda; Reona Aijima; Kazuaki Nonaka; Toshio Kukita; Songtao Shi; Fusanori Nishimura; Takayoshi Yamaza;
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports,volume 6 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: pmc: PMC4726054, doi: 10.1038/srep19286
  • Subject: Article
    mesheuropmc: stomatognathic diseases | stomatognathic system

Clinically, irreversible pulpitis is treated by the complete removal of pulp tissue followed by replacement with artificial materials. There is considered to be a high potential for autologous transplantation of human dental pulp stem cells (DPSCs) in endodontic treatme... View more
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