Tissue Factor–Factor VII Complex As a Key Regulator of Ovarian Cancer Phenotypes

Article English OPEN
Shiro Koizume; Yohei Miyagi;
  • Publisher: Libertas Academica
  • Journal: Biomarkers in Cancer, volume 7, issue Suppl 2, pages 1-13 (issn: 1179-299X, eissn: 1179-299X)
  • Publisher copyright policies & self-archiving
  • Identifiers: pmc: PMC4562604, doi: 10.4137/BIC.S29318
  • Subject: hypoxia | tissue factor | coagulation factor VII | ovarian cancer | Review | venous thromboembolism | RC254-282 | endometriosis | Neoplasms. Tumors. Oncology. Including cancer and carcinogens
    mesheuropmc: hemic and lymphatic diseases | cardiovascular diseases

Tissue factor (TF) is an integral membrane protein widely expressed in normal human cells. Blood coagulation factor VII (fVII) is a key enzyme in the extrinsic coagulation cascade that is predominantly secreted by hepatocytes and released into the bloodstream. The TF–fV... View more
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