Induction of a stable sigma factor SigR by translation-inhibiting antibiotics confers resistance to antibiotics

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Ji-Sun Yoo; Gyeong-Seok Oh; Sungweon Ryoo; Jung-Hye Roe;

Antibiotic-producing streptomycetes are rich sources of resistance mechanisms against endogenous and exogenous antibiotics. An ECF sigma factor sigma(R) (SigR) is known to govern the thiol-oxidative stress response in Streptomyces coelicolor. Amplification of this respo... View more
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