Induction of a stable sigma factor SigR by translation-inhibitingantibiotics confers resistance to antibiotics

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Yoo, Ji-Sun; Oh, Gyeong-Seok; Ryoo, Sungweon; Roe, Jung-Hye;

Antibiotic-producing streptomycetes are rich sources of resistance mechanisms against endogenous and exogenous antibiotics. An ECF sigma factor sigma(R) (SigR) is known to govern the thiol-oxidative stress response in Streptomyces coelicolor. Amplification of this respo... View more
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