The Streptococcus sanguinis competence regulon is not required for infective endocarditis virulence in a rabbit model.

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Jill E Callahan ; Cindy L Munro ; Todd Kitten
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 6, issue 10 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3198404, doi: 10.1371/journal.pone.0026403
  • Subject: Microbial Pathogens | Oral Medicine | Cardiovascular System | Gram Positive | Research Article | Biology | Bacterial Physiology | Dentistry | Infectious Diseases | Microbiology | Medicine | Bacterial Pathogens | Cardiovascular | Anatomy and Physiology | Streptococci | Bacterial Diseases | Pathogenesis | Q | Bacteriology | R | Microbial Physiology | Science | Streptococcal Infections | Acute Cardiovascular Problems

Streptococcus sanguinis is an important component of dental plaque and a leading cause of infective endocarditis. Genetic competence in S. sanguinis requires a quorum sensing system encoded by the early comCDE genes, as well as late genes controlled by the alternative s... View more
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