Recombination Accelerates Adaptation on a Large-Scale Empirical Fitness Landscape in HIV-1

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Moradigaravand, Danesh; Kouyos, Roger; Hinkley, Trevor; Haddad, Mojgan; Petropoulos, Christos J.; Engelstädter, Jan; Bonhoeffer, Sebastian;

Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory on the impact of recombination on the evolutionary dynamics of adapting populations, empirical evidence to test these theories is still scarce. We examined the effect of... View more