Multiple indices of diffusion identifies white matter damage in mild cognitive impairment and Alzheimer's disease.

Article English OPEN
Laurence O'Dwyer ; Franck Lamberton ; Arun L W Bokde ; Michael Ewers ; Yetunde O Faluyi ; Colby Tanner ; Bernard Mazoyer ; Des O'Neill ; Máiréad Bartley ; D Rónán Collins ; Tara Coughlan ; David Prvulovic ; Harald Hampel
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 6, issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3128090, doi: 10.1371/journal.pone.0021745
  • Subject: Neurobiology of Disease and Regeneration | Alzheimer Disease | Research Article | Biology | Cognitive Psychology | Memory | Neuroscience | Mental Health | Medicine | Psychiatry | Neuroimaging | Q | R | Psychology | Science | Dementia | Neurology
    • ddc: ddc:610

The study of multiple indices of diffusion, including axial (DA), radial (DR) and mean diffusion (MD), as well as fractional anisotropy (FA), enables WM damage in Alzheimer's disease (AD) to be assessed in detail. Here, tract-based spatial statistics (TBSS) were perform... View more
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