RAxML and FastTree: Comparing Two Methods for Large-Scale Maximum Likelihood Phylogeny Estimation

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Liu, Kevin; Linder, C. Randal; Warnow, Tandy;
(2011)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 6,issue 11 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3221724, doi: 10.1371/journal.pone.0027731
  • Subject: Computational Biology | Biostatistics | Algorithms | Computer Modeling | Research Article | Biology | Mathematics | Medicine | Q | R | Evolutionary Biology | Computer Science | Computer Applications | Science | Phylogenetics | Sequence Analysis | Software Engineering | Software Tools | Evolutionary Systematics | Molecular Systematics | Statistics

Statistical methods for phylogeny estimation, especially maximum likelihood (ML), offer high accuracy with excellent theoretical properties. However, RAxML, the current leading method for large-scale ML estimation, can require weeks or longer when used on datasets with ... View more
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