Involvement of pore-forming molecules in immune defense and development of the Mediterranean mussel (Mytilus galloprovincialis)

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Estévez-Calvar, Noelia; Romero, Alejandro; Figueras Huerta, Antonio; Novoa, Beatriz;
  • Publisher: Elsevier
  • Journal: Developmental & Comparative Immunology,volume 35,issue 10,pages1,017-1,031 (issn: 0145-305X)
  • Related identifiers: handle: 10261/54479, doi: 10.1016/j.dci.2011.03.023
  • Subject: Larval development | Perforin | Apextrin | Pore-forming molecules | Mediterranean mussel | Immune response | PAMPs | MACPF-domain-containing protein

The membrane attack complex and perforin (MACPF) superfamily is one of the largest families of poreforming molecules. Although MACPF proteins are able to destruct invading microbes, several MACPF proteins play roles in embryonic development, neural migration or tu... View more
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