Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration

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Sandra Gómez-López; Ana Valeria Martínez-Silva; Teresa Montiel; Daniel Osorio-Gómez; Federico Bermúdez-Rattoni; Lourdes Massieu; Diana Escalante-Alcalde;
(2016)

Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder, characterised by the progressive loss of midbrain dopaminergic neurons and a variety of motor symptoms. The gene coding for the phospholipid phosphatase 3, PLPP3 (formerly PPAP2B or LPP3), maps wit... View more
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