Activation of the "Splenocardiac Axis" by Electronic and Tobacco Cigarettes in Otherwise Healthy Young Adults

Article English OPEN
Boas, Z; Gupta, P; Moheimani, R; Bhetraratana, M; Yin, F; Peters, K; Gornbein, J; Araujo, J; Czernin, J; Middlekauff, H;
  • Publisher: eScholarship, University of California
  • Journal: volume 5,issue 17eissn: 2051-817X
  • Related identifiers: doi: 10.14814/phy2.13393, pmc: PMC5599858
  • Subject: Autonomic Nervous System | Tobacco and electronic cigarettes | electronic cigarettes | tobacco cigarettes | Toxins, Pollutants and Chemical Agents | FDG‐PET/CT | hematopoietic activation | Signalling Pathways | Vascular disease | Inflammation | Smoking | Original Research | Arterial inflammation | Positron emission tomography | Immunology | Cardiovascular Conditions, Disorders and Treatments

Abstract The “Splenocardiac Axis” describes an inflammatory signaling network underlying acute cardiac ischemia, characterized by sympathetic nerve stimulation of hematopoietic tissues, such as the bone marrow and spleen, which then release proinflammatory monocytes tha... View more