Regulation of hippocampal cannabinoid CB receptor actions by adenosine A receptors and chronic caffeine administration: implications for the effects of ∆-tetrahydrocannabinol on spatial memory

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Sousa , Vasco C.; Assaife-Lopes , Natália; Alexandre Ribeiro , Joaquim; Pratt , Judith A; Brett , Ros R; Sebastião , Ana Maria;
  • Publisher: Nature Publishing Group
  • Identifiers: doi: 10.1038/npp.2010.179
  • Subject: adenosine | Receptor Pharmacology | Learning & Memory | caffeine | hippocampus | cannabinoid | Neuropharmacology | GABA | THC

International audience; The cannabinoid CB receptor-mediated modulation of γ-aminobutyric acid (GABA) release from inhibitory interneurons is important for the integrity of hippocampal-dependent spatial memory. Although adenosine A receptors have a central role in fine-... View more
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