Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson's Disease

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Viereckel, Thomas; Dumas, Sylvie; Smith-Anttila, Casey J. A.; Vlcek, Bianca; Bimpisidis, Zisis; Lagerström, Malin C.; Konradsson-Geuken, Åsa; Wallén-Mackenzie, Åsa;
(2016)
  • Publisher: Univ Melbourne, Dept Anat & Neurosci, Melbourne, Vic 3010, Australia.
  • Journal: volume 6issn: 2045-2322, eissn: 2045-2322
  • Related identifiers: pmc: PMC5071886, doi: 10.1038/srep35203
  • Subject: Article | Neurology | Neurologi
    mesheuropmc: nervous system

The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) of the midbrain are associated with Parkinson's disease (PD), schizophrenia, mood disorders and addiction. Based on the recently unraveled heterogeneity within the VTA and SNc, where glutamate, GA... View more
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