Comparative Plasma Exposure and Lung Distribution of Two Human Use Commercial Azithromycin Formulations Assessed in Murine Model: A Preclinical Study

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Rivulgo, Virginia; Sparo, Mónica; Ceci, Mónica; Fumuso, Elida; Confalonieri, Alejandra; Delpech, Gastón; Sánchez Bruni, Sergio F.;
  • Publisher: Hindawi Publishing Corporation
  • Journal: BioMed Research International,volume 2,013 (issn: 2314-6133, eissn: 2314-6141)
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  • Related identifiers: pmc: PMC3773390, doi: 10.1155/2013/392010
  • Subject: LUNG | CIENCIAS AGRÍCOLAS | R | Research Article | GENERICS | Otras Ciencias Veterinarias | PHARMACOKINETICS | AZITHROMYCIN | Medicine | MICE | Article Subject | Ciencias Veterinarias

Azithromycin(AZM)therapeutic failure and relapses of patients treated with generic -35 formulations have been observed in clinical practice.The main goal of this research was 36 to compare in a pre-clinical study the serum exposure and lung tissue concentrationof 37 two... View more
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