Optimization of a Fluorescence-Based Assay for Large-Scale Drug Screening against Babesia and Theileria Parasites

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Rizk, Mohamed Abdo; El-Sayed, Shimaa Abd El-Salam; Terkawi, Mohamed Alaa; Youssef, Mohamed Ahmed; El Said, El Said El Shirbini; Elsayed, Gehad; El-Khodery, Sabry; El-Ashker, Maged; Elsify, Ahmed; Omar, Mosaab; Salama, Akram; Yokoyama, Naoaki; Igarashi, Ikuo; (2015)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 10,issue 4 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4411034, doi: 10.1371/journal.pone.0125276
  • Subject: Q | R | Research Article | Science | Medicine
    mesheuropmc: parasitic diseases

A rapid and accurate assay for evaluating antibabesial drugs on a large scale is required for the discovery of novel chemotherapeutic agents against Babesia parasites. In the current study, we evaluated the usefulness of a fluorescence-based assay for determining the ef... View more
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