The Cortisol Paradox of Trauma-Related Disorders : Lower Phasic Responses but Higher Tonic Levels of Cortisol Are Associated with Sexual Abuse in Childhood

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Schalinski, Inga; Elbert, Thomas; Steudte-Schmiedgen, Susann; Kirschbaum, Clemens;
(2015)
  • Publisher: Public Library of Science
  • Journal: volume 10,issue 8eissn: 1932-6203
  • Related identifiers: pmc: PMC4552952, doi: 10.1371/journal.pone.0136921
  • Subject: Research Article | Hydrocortisone, Child abuse, Post-traumatic stress disorder, Heart rate, Psychological stress, Hair, Blood pressure, Saliva
    • ddc: ddc:150

Objectives<br />Inconsistent findings exist for the activity of the hypothalamic-pituitary-adrenal (HPA) axis in patients with stress related disorders. Recent studies point towards early life stress as a potential modulator.<br /><br />Methods<br />We investigated the ... View more
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