Compensatory mechanisms in genetic models of neurodegeneration: are the mice better than humans?

Article English OPEN
Kreiner, Grzegorz (2015)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Cellular Neuroscience, volume 9 (issn: 1662-5102, eissn: 1662-5102)
  • Related identifiers: doi: 10.3389/fncel.2015.00056, doi: 10.3389/fncel.2015.00056/full, pmc: PMC4351629
  • Subject: Huntington’s disease | Neurosciences. Biological psychiatry. Neuropsychiatry | RC321-571 | Neuroscience | neurodegeneration | compensatory mechanisms | genetic models | Parkinson’s disease | Alzheimer’s disease | transgenic mice | Mini Review | compensation | transgenic mouse models

Neurodegenerative diseases are one of the main causes of mental and physical disabilities. Neurodegeneration has been estimated to begin many years before the first clinical symptoms manifest, and even a prompt diagnosis at this stage provides very little advantage for ... View more
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