Epithelial self-healing is recapitulated by a 3D biomimetic E-cadherin junction

Article, Other literature type English OPEN
Cohen, Daniel J.; Gloerich, Martijn; Nelson, W. James;
(2016)
  • Publisher: National Academy of Sciences
  • Related identifiers: pmc: PMC5187740, doi: 10.1073/pnas.1612208113
  • Subject: General | Wound healing | Biomaterial | Biomimetic | Cadherin | Journal Article | Collective migration | Biological Sciences

Epithelial monolayers undergo self-healing when wounded. During healing, cells collectively migrate into the wound site, and the converging tissue fronts collide and form a stable interface. To heal, migrating tissues must form cell-cell adhesions and reorganize from th... View more
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