Myocardin-related transcription factors are required for cardiac development and function

Article, Other literature type English OPEN
Mokalled, Mayssa H. ; Carroll, Kelli J. ; Cenik, Bercin K. ; Chen, Beibei ; Liu, Ning ; Olson, Eric N. ; Bassel-Duby, Rhonda (2015)
  • Publisher: Elsevier BV
  • Journal: Developmental Biology, volume 406, issue 2, pages 109-116 (issn: 0012-1606)
  • Related identifiers: doi: 10.1016/j.ydbio.2015.09.006, pmc: PMC4760630
  • Subject: Molecular Biology | Cell Biology | Developmental Biology | Article
    mesheuropmc: cardiovascular system

Myocardin-Related Transcription Factors A and B (MRTF-A and MRTF-B) are highly homologous proteins that function as powerful coactivators of serum response factor (SRF), a ubiquitously expressed transcription factor essential for cardiac development. The SRF/MRTF comple... View more
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