Macrophages form functional vascular mimicry channels in vivo
Barnett, Faith H.
Kiosses, William B.
- Publisher: Nature Publishing Group
(issn: 2045-2322, eissn: 2045-2322)
Macrophages, key cells of the innate immune system, are known to support angiogenesis but are not believed to directly form vessel walls. Here we show that macrophages structurally form primitive, NON-ENDOTHELIAL “vessels” or vascular mimicry (VM) channels in both tumor...