Macrophages form functional vascular mimicry channels in vivo

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Faith H. Barnett; Mauricio Rosenfeld; Malcolm Wood; William B. Kiosses; Yoshihiko Usui; Valentina Marchetti; Edith Aguilar; Martin Friedlander;

Macrophages, key cells of the innate immune system, are known to support angiogenesis but are not believed to directly form vessel walls. Here we show that macrophages structurally form primitive, NON-ENDOTHELIAL “vessels” or vascular mimicry (VM) channels in both tumor... View more
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