Repression of Meiotic Genes by Antisense Transcription and by Fkh2 Transcription Factor in Schizosaccharomyces pombe

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Chen, Huei-Mei; Rosebrock, Adam P.; Khan, Sohail R.; Futcher, Bruce; Leatherwood, Janet K.;
(2012)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 7,issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0029917, pmc: PMC3253116
  • Subject: Computational Biology | Research Article | Biology | Molecular Cell Biology | RNA | Developmental Biology | Microbiology | Cell Division | Medicine | Nucleic Acids | Q | R | Model Organisms | Science | Yeast and Fungal Models | Genomics
    mesheuropmc: fungi | urogenital system

In S. pombe, about 5% of genes are meiosis-specific and accumulate little or no mRNA during vegetative growth. Here we use Affymetrix tiling arrays to characterize transcripts in vegetative and meiotic cells. In vegetative cells, many meiotic genes, especially those ind... View more
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