Prospective cohort study using the breast cancer spheroid model as a predictor for response to neoadjuvant therapy – the SpheroNEO study

Article, Doctoral thesis OPEN
Halfter, Kathrin;;Ditsch, Nina;Kolberg, Hans-Christian;Fischer, Holger;Hauzenberger, Tanja;von Koch, Franz Edler;Bauerfeind, Ingo;von Minckwitz, Gunter;Funke, Ilona;Crispin, Alexander;Mayer, Barbara; (2017)
  • Publisher: Springer Nature
  • Journal: volume 15issn: 1471-2407, eissn: 1471-2407
  • Related identifiers: doi: 10.1186/s12885-015-1491-7, pmc: PMC4501185
  • Subject: Research Article | Breast cancer | Cellular response to anticancer drugs | in vitro diagnostics | Cancer Research | Oncology | Personalized medicine | Neoadjuvant chemotherapy | Genetics | Predicting treatment outcome | Medizinische Fakultät | Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie
    • ddc: ddc: | ddc:610 | ddc:600

Background Aim of this prospective study was to predict response to neoadjuvant therapy in breast cancer patients using an in vitro breast cancer spheroid model. Methods Three-dimensional spheroids were directly generated from fresh breast tumor biopsies of 78 patients ... View more
Share - Bookmark