Botulinum Toxin A for Oral Cavity Cancer Patients: In Microsurgical Patients BTX Injections in Major Salivary Glands Temporarily Reduce Salivary Production and the Risk of Local Complications Related to Saliva Stagnation

Article, Other literature type English OPEN
Corradino, Bartolo; Lorenzo, Sara Di; Moschella, Francesco;
(2012)
  • Publisher: Multidisciplinary Digital Publishing Institute
  • Journal: Toxins,volume 4,issue 11,pages956-961 (issn: 2072-6651, eissn: 2072-6651)
  • Related identifiers: doi: 10.3390/toxins4110956, pmc: PMC3509693
  • Subject: Botulinum toxin | salivary major glands | salivary production | Botulinum toxin, salivary production, oral cancer, free flap complications, saliva-related complications, forearm free flap, oro-cutaneous fistula, salivary major glands | Medicine | saliva-related complications | Article | oro-cutaneous fistula | R | Settore MED/19 - Chirurgia Plastica | forearm free flap | free flap complications | oral cancer

In patients suffering from oral cavity cancer surgical treatment is complex because it is necessary to remove carcinoma and lymph node metastasis (through a radical unilateral or bilateral neck dissection) and to reconstruct the affected area by means of free flaps. The... View more
  • References (11)
    11 references, page 1 of 2

    1. Conway, D.I.; Stockton, D.L.; Warnakulasuriya, K.A.A.S.; Ogden, G.; Macpherson, L.M.D. Incidence of oral and oropharyngeal cancer in the United Kingdom. Oral Oncol. 2006, 42, 586-592.

    2. Franceschi, S.; Bidoli, E.; Herrero, R.; Munoz, N. Comparison of cancers of the oral cavity and pharynx worldwide: Etiological clues. Oral Oncol. 2000, 36, 106-115.

    3. Salgado, C.J.; Mardini, S.; Chen, H.; Chen, S. Critical oropharyngocutaneous fistulas after microsurgical head and neck reconstruction: Indications for management using the tissueplug technique. Plast. Reconstr. Surg. 2003, 112, 957-963.

    4. Friedman, A.; Potulska, A. Quantitative assessment of parkinsonian sialorrhea and results of treatment with botulinum toxin. Parkinsonism Relat. Disord. 2001, 7, 329-332.

    5. Bothwell, J.E.; Clarke, K.; Dooley, J.M.; Gordon, K.E.; Anderson, R.; Wood, E.P.; et al. Botulinum toxin A as a treatment for excessive drooling in children. Pediatr. Neurol. 2002, 27, 18-22.

    6. Monnier, G.; Tatu, L.; Parratte, B.; Cosson, A.; Michel, F.; Metton, G. Sialorrhea, hyperhidrosis and botulinum toxin (In French). Ann. Readapt. Med. Phys. 2003, 46, 338-345.

    7. Arad, A.; Blitzer, A. Botulinum toxin in the treatment of autonomic nervous system disorders. Head Neck Surg. 2004, 15, 118-121.

    8. Ellies, M.; Laskawi, R.; Rohrbach-Volland, S.; Arglebe, C. Up-to-date report of botulinum toxin therapy in patients with drooling caused by different etiologies. J. Oral Maxillofac. Surg. 2003, 61, 454-457.

    9. Dogu, O.; Apaydin, D.; Sevim, S.; Talas, D.U.; Aral, M. Ultrasound-guided versus ''blind'' intraparotid injections of botulinum toxin-A for the treatment of sialorrhoea in patients with Parkinson's disease. Clin. Neurol. Neurosurg. 2004, 106, 93-96.

    10. Malpani, B.L.; Jaiswar, R.K.; Samuel, A.M. Noninvasive scintigraphic method to quantify unstimulated secretions from individual salivary glands. Auris Nasus Larynx 1999, 26, 453-456.

  • Similar Research Results (2)
  • Metrics
    No metrics available
Share - Bookmark