Relaxation of Selective Constraints Causes Independent Selenoprotein Extinction in Insect Genomes

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Chapple, Charles E.; Guigó, Roderic;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 3,issue 8 (eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0002968, pmc: PMC2500217
  • Subject: Research Article | Evolutionary Biology/Genomics | Selenocisteïna -- Aspectes genètics | Genetics and Genomics/Bioinformatics | Genetics and Genomics | Computational Biology/Comparative Sequence Analysis | Genetics and Genomics/Comparative Genomics | Genome | Selenocysteine | Computational Biology/Genomics | Biological extinction | Animals | Selenoproteins | Evolutionary Biology/Bioinformatics
    mesheuropmc: integumentary system

BACKGROUND: Selenoproteins are a diverse family of proteins notable for the presence of the 21st amino acid, selenocysteine. Until very recently, all metazoan genomes investigated encoded selenoproteins, and these proteins had therefore been believed to be essential for... View more
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