Markers of epithelial-to-mesenchymal transition reflect tumor biology according to patient age and Gleason score in prostate cancer

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Jędroszka, Dorota; Orzechowska, Magdalena; Hamouz, Raneem; Górniak, Karolina; Bednarek, Andrzej K.;
(2017)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 12,issue 12 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC5714348, doi: 10.1371/journal.pone.0188842
  • Subject: Research Article | Androgens | Anatomy | Exocrine Glands | Hormones | Prostate Gland | Mutation Databases | Oncology | Population Groupings | Genetics | People and Places | Cancers and Neoplasms | Database and Informatics Methods | Biology and Life Sciences | Biological Databases | Research and Analysis Methods | Estrogens | Medicine | Prostate Diseases | Age Groups | Q | Mutation | R | Prostate Cancer | Genitourinary Tract Tumors | Science | Urology | Biochemistry | Medicine and Health Sciences | Gene Expression

Introduction Prostate carcinoma (PRAD) is one of the most frequently diagnosed malignancies amongst men worldwide. It is well-known that androgen receptor (AR) plays a pivotal role in a vast majority of prostate tumors. However, recent evidence emerged stating that estr... View more
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