Evolutionary conservation of the ribosomal biogenesis factor Rbm19/Mrd1: implications for function.

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Kallberg, Yvonne; Segerstolpe, Åsa; Lackmann, Fredrik; Persson, Bengt; Wieslander, Lars;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 7,issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3440411, doi: 10.1371/journal.pone.0043786
  • Subject: Research Article | Biology | Molecular cell biology | Bioinformatics and Systems Biology | RNA | Proteomics | Medicine | Nucleic acids | Comparative Genomics | RNA processing | Q | R | Evolutionary Biology | Proteomic Databases | Bioinformatik och systembiologi | Proteins | Biochemistry | Science | Sequence Analysis

Ribosome biogenesis in eukaryotes requires coordinated folding and assembly of a pre-rRNA into sequential pre-rRNA-protein complexes in which chemical modifications and RNA cleavages occur. These processes require many small nucleolar RNAs (snoRNAs) and proteins. Rbm19/... View more
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