Evolutionary Conservation of the Ribosomal Biogenesis Factor Rbm19/Mrd1 : Implications for Function

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Kallberg, Yvonne ; Segerstolpe, Åsa ; Lackman, Fredrik ; Persson, Bengt ; Wieslander, Lars (2012)
  • Publisher: Stockholm University, Sweden
  • Journal: volume 7, issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3440411, doi: 10.1371/journal.pone.0043786
  • Subject: Research Article | Biology | Molecular cell biology | Bioinformatics and Systems Biology | RNA | Proteomics | Medicine | Nucleic acids | Comparative Genomics | RNA processing | Q | R | Evolutionary Biology | Proteomic Databases | Bioinformatik och systembiologi | Proteins | Science | Biochemistry | Sequence Analysis

Ribosome biogenesis in eukaryotes requires coordinated folding and assembly of a pre-rRNA into sequential pre-rRNA-protein complexes in which chemical modifications and RNA cleavages occur. These processes require many small nucleolar RNAs (snoRNAs) and proteins. Rbm19/... View more
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