Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice
- Publisher: Co-Action Publishing
Journal of Extracellular Vesicles,
(issn: 2001-3078, eissn: 2001-3078)
Cytology | splenic macrophage | exosome; Kupffer cell; splenic macrophage; lactadherin; Gaussia luciferase; clearance | Original Research Article | lactadherin | clearance | QH573-671 | Gaussia luciferase | exosome | Kupffer cell
Previous studies using B16BL6-derived exosomes labelled with gLuc–lactadherin (gLuc-LA), a fusion protein of Gaussia luciferase (a reporter protein) and lactadherin (an exosome-tropic protein), showed that the exosomes quickly disappeared from the systemic circulation a...