Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells

Other literature type, Article English OPEN
Zhong-Xin Xu; Jin-Ting He; Zong-Shu Li; Ting-Ting Chu; Jiao-Qi Wang; Chun-Li Mei; Jing Mang; (2013)
  • Publisher: MDPI AG
  • Journal: Molecules (issn: 1420-3049)
  • Related identifiers: doi: 10.3390/molecules181012977
  • Subject: Organic chemistry | QD241-441 | ischemic injury | activin A | ActA/Smads pathway | OGD
    mesheuropmc: bacteria | embryonic structures | macromolecular substances | fluids and secretions | technology, industry, and agriculture

Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD) injury have already been reported by... View more
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