Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HepG2 cells

Other literature type, Article English OPEN
de Diesbach, Philippe; Berens, C; N'Kuli, Francisca; Monsigny, M; Sonveaux, Etienne; Wattiez, R.; Courtoy, Pierre J.;
  • Publisher: Oxford University Press
  • Related identifiers: pmc: PMC102580
  • Subject: Blotting, Western | Oligodeoxyribonucleotides | Photoaffinity Labels | Receptors, Cell Surface | Subcellular Fractions | Tumor Cells, Cultured | Base Sequence | Protein Binding | Humans | Article
    mesheuropmc: respiratory system | hemic and immune systems

The low and unpredictable uptake and cytosolic transfer of oligonucleotides (ODN) is a major reason for their limited benefit. Improving the ODN potential for therapy and research requires a better understanding of their receptor-mediated endocytosis. We have undertaken... View more
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