Neutralisation of Interleukin-13 in Mice Prevents Airway Pathology Caused by Chronic Exposure to House Dust Mite
Tomlinson, Kate L.
Davies, Gareth C. G.
Sutton, Daniel J.
Palframan, Roger T.
- Publisher: Public Library of Science
(issn: 1932-6203, eissn: 1932-6203)
Q | Immunology/Immunomodulation | R | Research Article | Science | Respiratory Medicine/Asthma | Medicine | Immunology/Allergy and Hypersensitivity
mesheuropmc: respiratory system | respiratory tract diseases
BACKGROUND: Repeated exposure to inhaled allergen can cause airway inflammation, remodeling and dysfunction that manifests as the symptoms of allergic asthma. We have investigated the role of the cytokine interleukin-13 (IL-13) in the generation and persistence of airwa...