Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide

Article OPEN
Kurmis, Alexis A; Dervan, Peter B;
(2019)

Abstract The crucial role of androgen receptor (AR) in prostate cancer development is well documented, and its inhibition is a mainstay of prostate cancer treatment. Here, we analyze the perturbations to the AR cistrome caused by a minor groove binding molecule that is ... View more
Share - Bookmark