Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation

Article English OPEN
Gal, Csenge ; Murton, Heather E. ; Subramanian, Lakxmi ; Whale, Alex J. ; Moore, Karen M. ; Paszkiewicz, Konrad ; Codlin, Sandra ; Bähler, Jürg ; Creamer, Kevin M. ; Partridge, Janet F. ; Allshire, Robin C. ; Kent, Nicholas A. ; Whitehall, Simon K. (2016)
  • Publisher: Nature Publishing Group
  • Journal: volume 17, issue 1, pages 79-93 (issn: 1469-221X, eissn: 1469-3178)
  • Related identifiers: pmc: PMC4718406, doi: 10.15252/embr.201540476
  • Subject: Molecular Biology | QH426 | bromodomain AAA‐ATPases | Chromatin | Article | Abo1 | Chromatin, Epigenetics, Genomics & Functional Genomics | Schizosaccharomyces pombe | Bromodomain AAA-ATPases | Genetics | /dk/atira/pure/subjectarea/asjc/1300/1311 | Nucleosome mapping | /dk/atira/pure/subjectarea/asjc/1300/1312 | Biochemistry | /dk/atira/pure/subjectarea/asjc/1300/1303 | Articles

<p>Maintenance of the correct level and organisation of nucleosomes is crucial for genome function. Here, we uncover a role for a conserved bromodomain AAA-ATPase, Abo1, in the maintenance of nucleosome architecture in fission yeast. Cells lacking abo1<sup>+</sup> exper... View more