Abo1, a conserved bromodomain AAA‐ATPase, maintains global nucleosome occupancy and organisation

Article English OPEN
Gal, Csenge; Murton, Heather E.; Subramanian, Lakxmi; Whale, Alex J.; Moore, Karen M.; Paszkiewicz, Konrad; Codlin, Sandra; Bähler, Jürg; Creamer, Kevin M.; Partridge, Janet F.; Allshire, Robin C.; Kent, Nicholas A.; Whitehall, Simon K.;
  • Publisher: John Wiley and Sons Inc.
  • Journal: EMBO Reports, volume 17, issue 1, pages 79-93 (issn: 1469-221X, eissn: 1469-3178)
  • Publisher copyright policies & self-archiving
  • Identifiers: pmc: PMC4718406, doi: 10.15252/embr.201540476
  • Subject: Molecular Biology | QH426 | chromatin | bromodomain AAA‐ATPases | Abo1 | Article | Chromatin, Epigenetics, Genomics & Functional Genomics | Schizosaccharomyces pombe | Bromodomain AAA-ATPases | Genetics | /dk/atira/pure/subjectarea/asjc/1300/1311 | nucleosome mapping | /dk/atira/pure/subjectarea/asjc/1300/1312 | Biochemistry | /dk/atira/pure/subjectarea/asjc/1300/1303 | Articles

<p>Maintenance of the correct level and organisation of nucleosomes is crucial for genome function. Here, we uncover a role for a conserved bromodomain AAA-ATPase, Abo1, in the maintenance of nucleosome architecture in fission yeast. Cells lacking abo1<sup>+</sup> exper... View more