Transplantation Tolerance Induction: Cell Therapies and Their Mechanisms

Article English OPEN
Scalea, Joseph R. ; Tomita, Yusuke ; Lindholm, Christopher R. ; Burlingham, William (2016)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology, volume 7 (issn: 1664-3224, eissn: 1664-3224)
  • Related identifiers: pmc: PMC4779899, doi: 10.3389/fimmu.2016.00087, doi: 10.3389/fimmu.2016.00087/full
  • Subject: CD34+ cells | regulatory mechanisms | RC581-607 | MDSC | Treg | Review | transplantation tolerance | Immunologic diseases. Allergy | HSCT | Immunology | regulatory myeloid cells

Cell based therapies have been studied extensively in the context of transplantation tolerance induction. The most successful protocols have relied on transfusion of bone marrow prior to the transplantation of a renal allograft. However, it is not clear that stem cells ... View more
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