publication . Article . 2020

Adherence to and persistence with zoledronic acid treatment for osteoporosis-reasons for early discontinuation

Anna Spångeus; Simon Johansson; Mischa Woisetschläger;
Open Access English
  • Published: 01 Apr 2020
  • Publisher: Linköpings universitet, Avdelningen för diagnostik och specialistmedicin
  • Country: Sweden
This retrospective study reports 81% long-term (> 3 years) adherence to and 77% persistence with zoledronic acid (ZA) treatment in osteoporosis patients, with ZA being costfree for patients. Eight percent of patients discontinued treatment because of adverse events (AEs), with a tendency of higher discontinuation rate in older patients. Purpose This study investigated (1) long-term adherence to and persistence with ZA treatment in a real-world setting, (2) extent to which an adverse reaction to ZA impacted on adherence and persistence, and (3) whether there were sex or age differences in patients that had early treatment termination (ETT) due to AEs and t...
free text keywords: Osteoporosis; Bisphosphonate; Zoledronic acid; Adherence; Discontinuation; Adverse event, Occupational Therapy, Arbetsterapi, Orthopedics and Sports Medicine, Original Article, Osteoporosis, Bisphosphonate, Zoledronic acid, Adherence, Discontinuation, Adverse event
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