Simulating Sleep Apnea by Exposure to Intermittent Hypoxia Induces Inflammation in the Lung and Liver

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da Rosa, Darlan Pase; Forgiarini, Luiz Felipe; Baronio, Diego; Feijó, Cristiano Andrade; Martinez, Dênis; Marroni, Norma Possa;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Mediators of Inflammation,volume 2,012 (issn: 0962-9351, eissn: 1466-1861)
  • Related identifiers: pmc: PMC3513737, doi: 10.1155/2012/879419
  • Subject: RB1-214 | Pathology | Research Article | Article Subject

Sleep apnea is a breathing disorder that results from momentary and cyclic collapse of the upper airway, leading to intermittent hypoxia (IH). IH can lead to the formation of free radicals that increase oxidative stress, and this mechanism may explain the association be... View more
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