In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

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Buckley, Suzanne M. K. ; Delhove, Juliette M. K. M. ; Perocheau, Dany P. ; Karda, Rajvinder ; Rahim, Ahad A. ; Howe, Steven J. ; Ward, Natalie J. ; Birrell, Mark A. ; Belvisi, Maria G. ; Arbuthnot, Patrick ; Johnson, Mark R. ; Waddington, Simon N. ; McKay, Tristan R. (2015)
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports, volume 5 (eissn: 2045-2322)
  • Related identifiers: doi: 10.1038/srep11842, pmc: PMC4490336
  • Subject: Extracellular signalling molecules | Bioluminescence imaging | Article

The application of transcription factor activated luciferase reporter cassettes in vitro is widespread but potential for in vivo application has not yet been realized. Bioluminescence imaging enables non-invasive tracking of gene expression in transfected tissues of liv... View more
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