In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

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Buckley, S. M.; Delhove, J. M.; Perocheau, D. P.; Karda, R.; Rahim, A. A.; Howe, S. J.; Ward, N. J.; Birrell, M. A.; Belvisi, M. G.; Arbuthnot, P.; Johnson, M. R.; Waddington, S. N.; McKay, T. R.;
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports,volume 5 (eissn: 2045-2322)
  • Related identifiers: doi: 10.1038/srep11842, pmc: PMC4490336
  • Subject: Extracellular signalling molecules | Bioluminescence imaging | Article

The application of transcription factor activated luciferase reporter cassettes in vitro is widespread but potential for in vivo application has not yet been realized. Bioluminescence imaging enables non-invasive tracking of gene expression in transfected tissues of liv... View more
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