Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

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Fivelman, Quinton L; Butcher, Geoffrey A; Adagu, Ipemida S; Warhurst, David C; Pasvol, Geoffrey;
  • Publisher: BioMed Central
  • Journal: Malaria Journal,volume 1,pages1-1 (eissn: 1475-2875)
  • Related identifiers: pmc: PMC111499, doi: 10.1186/1475-2875-1-1
  • Subject: Case Report
    mesheuropmc: parasitic diseases

We report the first in vitro and genetic confirmation of Malarone® (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum acquired in Africa. On presenting with malaria two weeks after returning from a 4-week visit to Lagos, Nigeri... View more
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