Computational models of neuron-astrocyte interaction in epilepsy

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Volman, Vladislav; Bazhenov, Maxim; Sejnowski, Terrence J.;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Computational Neuroscience,volume 6 (issn: 1662-5188, eissn: 1662-5188)
  • Related identifiers: pmc: PMC3459315, doi: 10.3389/fncom.2012.00058
  • Subject: trauma | Review Article | regulatory signaling | inflammation | Neuroscience | epileptogenesis | astrocytes
    mesheuropmc: nervous system

Astrocytes actively shape the dynamics of neurons and neuronal ensembles by affecting several aspects critical to neuronal function, such as regulating synaptic plasticity, modulating neuronal excitability, and maintaining extracellular ion balance. These pathways for a... View more
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