Diffusion-Weighted Magnetic Resonance Imaging Allows Noninvasive In Vivo Monitoring of the Effects of Combretastatin A-4 Phosphate after Repeated Administration

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Thoeny, Harriet C.; De Keyzer, Frederik; Chen, Feng; Vandecaveye, Vincent; Verbeken, Erik K.; Ahmed, Bisan; Sun, Xihe; Ni, Yicheng; Bosmans, Hilde; Hermans, Robert; van Oosterom, Allan; Marchal, Guy; Landuyt, Willy;
  • Publisher: Elsevier
  • Journal: Neoplasia: An International Journal for Oncology Research,volume 7,issue 8,pages779-787 (issn: 1476-5586, eissn: 1522-8002)
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  • Related identifiers: doi: 10.1593/neo.04748
  • Subject: necrosis | CA4-P | RC254-282 | anticancer therapy | vascular targeting | DW-MRI | Neoplasms. Tumors. Oncology. Including cancer and carcinogens

The noninvasive assessment of anticancer treatment efficacy is very important for the improvement of therapeutic window. The purpose of the present study was to evaluate the antitumoral effects of the vascular targeting agent, combretastatin A-4 phosphate (CA-4-P), at s... View more
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