Highly Perturbed pKa Values in the Unfolded State of Hen Egg White Lysozyme

Article, Other literature type English OPEN
Bradley, John; O'Meara, Fergal; Farrell, Damien; Nielsen, Jens Erik;

The majority of pKa values in protein unfolded states are close to the amino acid model pKa values, thus reflecting the weak intramolecular interactions present in the unfolded ensemble of most proteins. We have carried out thermal denaturation measurements on the WT an... View more
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