Strains of Rodents and the Pharmacology of Learning and Memory
- Publisher: Hindawi Publishing Corporation
(issn: 2090-5904, eissn: 1687-5443)
Neurosciences. Biological psychiatry. Neuropsychiatry | RC321-571 | Article
Mendelian genetic tools have extensively
been used to improve the description of the
pharmacological mechanisms involved in
learning and memory. The first part of this
short review describes experiments involving
the bidirectional selection of rats or mice for
extreme behavioral characteristics or for
sensitivity to pharmacological treatments.
The second part focuses specifically on inbreeding.
In conclusion, the advantages and
the limits of a Mendelian pharmacogenetic
approach of learning and memory are