Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences.

Article English OPEN
Michael J McDonald; Wei-Chi Wang; Hsien-Da Huang; Jun-Yi Leu; (2011)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Biology,volume 9,issue 6 (issn: 1544-9173, eissn: 1545-7885)
  • Related identifiers: pmc: PMC3114760, doi: 10.1371/journal.pbio.1000622
  • Subject: Evolutionary Biology/Evolutionary and Comparative Genetics | Research Article | Evolutionary Biology/Human Evolution | Evolutionary Biology/Genomics | Genetics and Genomics/Genomics | Genetics and Genomics/Bioinformatics | Genetics and Genomics/Comparative Genomics | Molecular Biology/Molecular Evolution | QH301-705.5 | Microbiology/Microbial Evolution and Genomics | Evolutionary Biology/Microbial Evolution and Genomics | Molecular Biology/DNA Repair | Molecular Biology/Bioinformatics | Genetics and Genomics/Population Genetics | Biology (General) | Genetics and Genomics/Microbial Evolution and Genomics
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The genome-sequencing gold rush has facilitated the use of comparative genomics to uncover patterns of genome evolution, although their causal mechanisms remain elusive. One such trend, ubiquitous to prokarya and eukarya, is the association of insertion/deletion mutatio... View more
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